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Título: | Chronic periodontitis, inflammatory cytokines, and interrelationship with other chronic diseases |
Autores: | Cardoso, Elsa Reis, Cátia Céspedes, Maria Cristina |
Palavras Chave: | Inflammation; immune system; periodontium; chronic noncommunicable diseases; periodontal diseases |
Data: | 25-Oct-2017 |
Editora: | Postgraduate Medicine |
Resumo: | Periodontal diseases, such as chronic periodontitis, share common inflammatory risk factors with other
systemic and chronic inflammatory disorders. Mucosal tissues, such as oral epithelia, are exposed to
environmental stressors, such as tobacco and oral bacteria, that might be involved in promoting a
systemic inflammatory state. Conversely, chronic disorders can also affect oral health. This review will
summarize recent evidence for the interrelationship between chronic periodontitis and other prevalent
chronic diseases such as cardiovascular diseases, diabetes, cancer and chronic respiratory diseases. The
association with pregnancy is also included due to possible obstetric complications. We will focus on
inflammatory cytokines such as TNF-alpha, IL-1, and IL-6, because they have been shown to be
increased in patients with chronic periodontitis, in patients with chronic systemic diseases, and in
patients with both chronic periodontitis and other chronic diseases. Therefore, an imbalance towards a
proinflammatory immune response could underline a bidirectional link between chronic periodontitis
and other chronic diseases. Finally, we highlight that a close coordination between dental and other
health professionals could promote oral health and prevent or ameliorate other chronic diseases. |
URI: | http://hdl.handle.net/10314/3930 |
ISSN: | DOI: 10.1080/00325481.2018.1396876 |
Aparece nas Colecções: | Artigos em Revista Internacional (ESS)
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