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Utilize este identificador para referenciar este registo:
http://hdl.handle.net/10314/4430
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| Título: | Antioxidant Status, Antidiabetic Properties and Effects on Caco-2 Cells of Colored and Non-Colored Enriched Extracts of Sweet Cherry Fruits |
| Autores: | Gonçalves, Ana
Rodrigues, Márcio
Santos, Adriana
Alves, Gilberto
Silva, Luís |
| Palavras Chave: | sweet cherry
anthocyanins
non-colored phenolics
antioxidant activity
erythrocytes protection
Caco-2 cells |
| Data: | 2018 |
| Relatório da Série N.º: | 1688 |
| Resumo: | This study aimed to compare three different extracts of Saco sweet cherry, namely the non-colored fraction, colored fraction, and total extract concerning phenolic composition, antioxidant and antidiabetic potential, and erythrocytes’ protection and effects on Caco-2 cells. Twenty-two phenolic compounds were identified using high-performance liquid chromatography with diode-array detection. Hydroxycinnamic acids were the most predominant in both the non-colored fraction and total extract, while cyanidin-3-O-rutinoside was the main anthocyanin found in the colored fraction. The total extract was the most effective against 1,1-diphenyl-2-picrylhydrazyl, nitric oxide, and superoxide radicals, and in the inhibition of α-glucosidase enzyme. The colored fraction revealed the best activity against hemoglobin oxidation and hemolysis. Regarding to Caco-2 cells, the colored extract exhibited the highest cytotoxic effects, while the total extract was the most efficient in protecting these cells against oxidative damage induced by tert-butyl hydroperoxide. |
| URI: | http://hdl.handle.net/10314/4430 |
| Aparece nas Colecções: | Artigos em Revista Internacional (ESS)
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Ficheiros deste Registo:
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Descrição |
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| Gonçalves et al., 2018.pdf | | 192Kb | Adobe PDF | Ver/Abrir | |
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