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Utilize este identificador para referenciar este registo: http://hdl.handle.net/10314/7258

Título: Assessment of Potentially Inappropriate Medications Using the EU (7)-PIM List, in a Sample of Portuguese Older Adults' Residents in Nursing Homes
Autores: Plácido, Ana
Aguiar, Ana
Piñeiro-Lamas, María
Varallo, Fabiana
Figueiras, Adolfo
Herdeiro, Maria
Roque, Fátima
Palavras Chave: elderly
institutionalized older adults
medication profile
prescription
Data: 13-Jul-2022
Resumo: Abstract: Prescription of potentially inappropriate medication (PIM) in older adults is associated with poor clinical outcomes. The EU (7)-PIM list was created for the European market to improve pharmacotherapy in older adults. Purpose: This work aims to characterize the medication profile and assess the presence of PIM, using the EU (7)-PIM list in older adults' residents at nursing homes. Methods: Retrospective data were collected from the anonymized nursing home records. After PIM identification, a descriptive analysis was performed, and a generalized linear model for dependent negative binomial-type variables was constructed to assess the risk of PIM. Results: Of the 210 participants (mean age 85.10), 82.40% were polymedicated. PIM was observed in 86.4% participants (mean per patient = 2.30± 0.10). The most common PIM were proton pump inhibitors (n = 121, 57.62%), followed by anxiolytics (n = 96, 45.71%). 64.30% of all patients take 2-4 PIM and 5.80% take five or more PIM. The occurrence of PIM is influenced by the number of prescribed medicines (RR 1.14; 95% CI 1.1.-1.17) and the presence of digestive system diseases (RR 1.05; 95% CI 1.0-1.09). Conclusion: The high prevalence of PIM observations highlights the necessity of the implementation of guidelines to prevent PIM.
URI: http://hdl.handle.net/10314/7258
ISSN: 35860675
Aparece nas Colecções:Artigos em Revista Internacional (ESS)

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